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KMID : 1151920210030020053
Chronobiology in Medicine
2021 Volume.3 No. 2 p.53 ~ p.56
Circadian Rhythm and Primary Headache
Im Hee-Jin

Abstract
The comorbidity of sleep and headache disorders has been recognized for centuries. Among various factors of sleep that interrupt or aggravate headaches?including sleep duration, altered arousal system, sleep disordered breathing, and mood?circadian rhythm disorder can be an important factor in patients with primary headache. There is overwhelming evidence that primary headaches such as migraines and cluster headaches have periodicity and seasonal variation and are associated with chronobiological disorder through sharing a biological mechanism and the involvement of hypothalamus. This paper explores the relationship between headache and circadian rhythm. To cope with the reciprocal relationship, consideration of circadian rhythm in managing the patient with headache can reduce the severity and frequency of primary headache, leading to better quality of life for the patient.
KEYWORD
Sleep, Circadian rhythm, Primary headache disorders, Migraine, Chronotype
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